ADVANCED WATER DEPLETION*

15 water shedding compounds*
Helps remove subcutaneous water between muscles to help you achieve a ripped, dry look*
Includes an electrolyte replenishment matrix
Helps improve tissue firmness*
Good source of dietary fiber, folic acid, vitamin C, vitamin E, vitamin B6, and several minerals

Description

Are you holding a that bit of subcutaneous water that you just can’t get rid of? Are you getting ready for a photo shoot? A competition? Or just don’t want to have that bloated look going to the beach or a wedding?

If so, H2O Revolution™ is right up your alley. Many water reduction pills on the market deplete water from ALL compartments of the body. This means it will come out of your muscle as well as fat and skin subcutaneously.

When this happens the muscles will appear thinner and you won’t look as good even WITHOUT the subcutaneous water. H2O Revolution™ will assist in pulling out subcutaneous water.

This will allow you to keep your curves and muscular fullness while being able to see it better without the bloat blurring your lines! A look at a few key ingredients in H2O Revolution™ will show you why.

Dandelion Root Extract – A time tested and proven diuretic that increases urinary expulsion and eliminates excess water.
Caffeine Anhydrous, Yerba Matte, & Green Tea – These ingredients not only acts as potent thermogenics but also effective diuretics (water eliminating).
Asparagus Extract – Often used with lots of fluids as “irrigation therapy” to increase urine output.
Uva-Ursi Root - Helps to tighten upper layers of the mucous membrane – relieving irritation and improving tissue firmness.
Juniper Extract – Acts as a diuretic by increasing glomerular filtration rate.

Bar none H2O Revolution™ is the #1 water depletion tool on the market.

Using a matrix that combines the industries top herbal diuretics, H2O Revolution™ will help remove subcutaneous water from in between your muscles to help you achieve that ripped, dry, and toned look.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Supplement Facts

Best Body Water Reduction Diuretic Supplement

Ingredient Profile

H2O DEPLETION MATRIX

Celery Seed Extract

Celery seed oil is a supplement containing a high amount of volatile compounds known as phthalides. These compounds, as well as the major component Sedanolide, appear to have general antioxidative properties and have traditionally been used as a diuretic.

Celery seed extract may help improve overall wellness, joint support, and digestive health.

Taraxacum Officinale Leaf Extract (Dandelion)

Taraxacum officinale, also known as dandelion, is a vegetable that has a diuretic (water loss) effect when ingested.

It is also a source of potassium and thereby helps replace diuresis-induced losses.
Dandelion may help ease digestion by increasing the rate at which food leaves the stomach and enters the small intestine.
A study conducted by Clare et al. (2009) found dandelion three times a day in otherwise healthy subjects reported an increase in urination frequency relative to the same subjects the day before and after supplementation.

Uva-Ursi Root

Uva-Ursi is an herbal compound which has the effects of a mild diuretic and astringent (anti-inflammatory).

It helps to reduce accumulation of uric acid in the bladder and help the overall health and productivity of the urinary tract.
Uva-Ursi may also help reduce high blood pressure and bloating.
Its anti-inflammatory effects can help to tighten upper layers of the mucous membrane – relieving irritation and improving tissue firmness.

Caffeine Anhydrous

Caffeine Anhydrous is simply caffeine with no water (around .05%). This has been shown to make caffeine anhydrous more potent because the body will absorb it more readily.

Caffeine acts as a mild diuretic (water loss).
Although caffeine can affect a wide variety of motor and mental functions it is most commonly used to improve endurance exercise, focus, and cognitive performance, and improve energy levels.
Caffeine has also been shown to have a thermogenic effect (heating/calorie burning) at rest and may increase the use of fats for fuel during exercise.
According to the research higher doses of caffeine, in the 250-450mg range, are needed to provide an ergogenic benefit.
In a study conducted by Astorino et al. (2010), active men given caffeine before resistance training were able to increase maximal torque, power, and volume by 5-8%

Yerba Matte

Yerba matte is a south American plant that offers the stimulative effects of coffee with the health benefits of tea. It contains caffeine, theobromine, theophylline, and numerous antioxidants.

Yerba Matte may prevent lipid oxidation, which decreases the number of free radicals produced in the body.
It has been shown to reduce fat as well as lower LDL cholesterol.
Human studies have shown a reduction in inflammation when supplementing with Yerba Matte.
A 2009 study performed by the Federal University of Santa Catarina noted Yerba Mate ingestion for 20-40 days, in healthy individuals, was shown to reduce body fat content as well as lower LDL cholesterol. In turn, the reduction of body fat and LDL cholesterol levels aided in lowering systolic blood pressure.

Green Tea

Green Tea Extract is an herbal derivative from green tea leaves, containing antioxidant ingredients and caffeine.

This extract contains high amounts of catechins, including EGCG which helps with the metabolism of fat at rest and during exercise performance.
Green tea also reduces the formation of free radicals in the body which protect cells and molecules from damage.
A meta-analysis of 11 studies looking at green tea consumption over a period of 12 weeks minimum noted, on average, 1.31kg weight loss.

Asparagus Extract

Throughout history asparagus's most widespread health application has been for the support of fluid balance and cleansing.

Asparagus is a good source of dietary fiber, folic acid, vitamin C, vitamin E, vitamin B6, and several minerals.
Asparagus is used along with lots of fluids as “irrigation therapy” to increase urine output.
It is also used to treat urinary tract infections and other conditions of the urinary tract that cause pain and swelling.

Watermelon Extract

Watermelon extract is high in vitamin C and citrulline. It is often used to improve hydration levels and replenish depleted electrolytes.

At the same time, watermelon extract can increase urine output, making it an effective diuretic.
Watermelon extract also has additional benefits such as soothing sore muscles and lowering blood pressure.
According to a new study in the Journal of Agricultural Food and Chemistry, drinking watermelon juice before a hard workout helped reduce athletes' heart rate and next-day muscle soreness. That's because watermelon is rich in an amino acid called L-citrulline, which the body converts to L-arginine, an essential amino acid that helps relax blood vessels and improve circulation.

Ginger Root

Ginger is a spice that can reduce nausea and ease digestion quite effectively.

It is commonly used to treat a myriad of stomach problems. It helps to reduce everything from heartburn to gas and diarrhea.
A meta-analysis conducted by Ernst et al. (2000) found ginger was able to reduce nausea induced by seasickness, morning sickness, and chemotherapy induced sickeness.

Juniper Extract

Juniper extract helps fight inflammation and various GI issues including upset stomach, heartburn, flatulence, bloating, and loss of appetite.

Juniper extract has been used as a diuretic. This activity is most likely due to the action of terpinen-4-ol, which is known to increase renal glomerular filtration rate.

Buchu Extract

Buchu is harvested from the dried leaves obtained from three species of Barosma.

Historically, buchu has been used to treat inflammation, kidney and urinary tract infections; and as a diuretic.

Taurine

Taurine has a myriad of benefits. From helping the body to metabolize fat, improving insulin sensitivity, raising testosterone levels, as an antioxidant, higher performance and quicker recovery during athletic training and increasing cardiovascular health… it goes without saying that Taurine is a great ingredient to have in your wheelhouse

Zhang et al. (2004) found that individuals who supplemented with taurine for 1 week before an exhaustive exercise bout significantly improved time to exhaustion, VO2 max, and maximal workload. It also decreased exercise induced DNA damage.

Astragalus Centralpinus

Astragalus is considered an adaptogenic herb that helps protect the body against various stresses, including mental, emotional, and physical stress.

Astragalus also demonstrates the capability, via adipocytes (fat cells), to improve glucose metabolism and diabetic symptoms through a variety of mechanisms.
Astragalus can enhance exercise endurance and performance. Studies using the herb found that supplementation reduced exercise-induced accumulation of the byproducts blood lactate and ammonia. This resulted in less fatigue and translates into improved exercise performance.

Chromium Polynicotinate

Chromium is a mineral our bodies use in small amounts for normal body functions, such as digesting food.

Chromium helps to move blood sugar from the bloodstream into the cells to be used as energy and to turn fats, carbohydrates, and proteins into energy.
Chromium also helps regulate fat and cholesterol in the body and may reduce food craving.
A study conducted by Anton et al. (2008) found that subjects supplementing with chromium over an 8 week period reduced hunger, cravings, and lost more weight compared to a placebo group.

ELECTROLYTE REPLENISHMENT MATRIX

Potassium

Potassium is a mineral found in varying amounts in almost all foods.

It is needed for building and keeping strong bones.
It also helps control the amount of calcium in the body and urine.
If potassium levels get too high or too low, the heart and nervous system completely shut down. Many people in the U.S. often fail to obtain optimal amounts of this nutrient and pay a health cost for it.

Calcium

Calcium is an electrolyte that is necessary for many functions, especially muscle contraction.

Therefore, the level of calcium in the blood has to be kept in a narrow range at all times.
If the blood calcium level drops, then the bones will release calcium until an optimal level is once again achieved. However, this compromises the strength of the bones.
Importantly, calcium is lost in sweat, so prolonged exercise requires calcium replenishment.

Magnesium

Magnesium is an essential mineral and electrolyte. It is involved in protein synthesis, ATP formation, metabolism of carbohydrates and fats, and bone strength.

Magnesium deficiencies are the second most common deficiency in developed countries. A lack of magnesium will raise blood pressure and reduce insulin sensitivity.
Increases in free and total testosterone have been noted in sedentary and athletic populations when supplementing with magnesium supplementation. It also acts as a muscle relaxer and may improve aerobic performance.
Brilla et al. (1992) discovered 26 untrained subjects who participated in a 7-week strength training program in conjunction with magnesium supplementation were able to increase testosterone relative to baseline.

FAQs

Q: What is the best way to take H2O Revolution?

A: As a dietary supplement, take 1 Serving (3 Capsules) in the morning on an empty stomach & 1 serving before your mid-day meal.

Q: What is a diuretic?

A: A diuretic is a substance or ingredient, such as the ones in H2O revolution, that promote the expulsion of body fluids via urine. Higher urine output lessens total body water retention.

Q: What other MuscleSport products do you recommend stacking with H2O Revolution?

A: For your weight loss and fat loss goals, we recommend stacking H2O Revolution with Thermal Revolution, Detox Revolution, and LipoSlim Revolution.

References

Celery Seed Extract

1. Ahmed B, Alam T, Varshney M, Khan SA. Hepatoprotective activity of two plants belonging to the Apiaceae and the Euphorbiaceae family. J Ethnopharmacol. 2002 Mar;79(3):313-6.

2. Al-Howiriny T, Alsheikh A, Alqasoumi S, Al-Yahya M, ElTahir K, Rafatullah S. Gastric antiulcer, antisecretory and cytoprotective properties of celery (Apium graveolens) in rats. Pharm Biol. 2010 Jul;48(7):786-93.

3. Atta AH, Alkofahi A. Anti-nociceptive and anti-inflammatory effects of some Jordanian medicinal plant extracts. J Ethnopharmacol. 1998;60:117-124.

4. Banerjee S, Sharma R, Kale RK, Rao AR. Influence of certain essential oils on carcinogen-metabolizing enzymes and acid-soluble sulfhydryls in mouse liver. Nutr Cancer. 1994;21:263-269. Abstract.

5. Boffa MJ, Gilmour E, Ead RD. Case report. Celery soup causing severe phototoxicity during PUVA therapy [letter]. Br J Dermatol. 1996;135(2):334.

6. Cheung MC, Lin LY, Yu TH, Peng RY. Hypolipidemic and antioxidant activity of mountian celery seed essential oils. J Agric Food Chem. 2008;56(11):3997-4003.

Dandelion

1. Lee et al. 2012; Effects of Taraxacum officinale on fatigue and immunological parameters in mice.

2. Jeon et al. 2008; Anti-inflammatory activity of Taraxacum officinale.

3. Choi et al. 2010; Hypolipidemic and antioxidant effects of dandelion (Taraxacum officinale) root and leaf on cholesterol-fed rabbits.

4. Turski et al. 2011; Distribution, synthesis, and absorption of kynurenic acid in plants.

5. Domitrovic et al. 2010; Antifibrotic activity of Taraxacum officinale root in carbon tetrachloride-induced liver damage in mice.

6. Chaterjee et al 2011; The efficacy of dandelion root extract in inducing apoptosis in drug-resistant human melanoma cells.

7. Ovadje et al 2012; Efficient induction of extrinsic cell death by dandelion root extract in human chronic myelomonocytic leukemia (CMML) cells.

Uva-Ursi

1. Beaux D, Fleurentin J, Mortier F. Effect of extracts of Orthosiphon stamineus Benth, Hieracium pilosella L., Sambucus nigra L. and Arctostaphylos uva-ursi (L.) Spreng. in rats. Phytother Res. 1999;13(3):222-5.

2. Chauhan B, Yu C, Krantis A, Scott I, Arnason JT, Marles RJ, Foster BC. In vitro activity of uva-ursi against cytochrome P450 isoenzymes and P-glycoprotein. Can J Physiol Pharmacol. 2007;85(11):1099-107.

3. Grases F, Melero G, Costa-Bauza A, Prieto R, March JG Urolithiasis and phytotherapy. Int Urol Nephrol. 1994;26(5):507-11.

4. Head KA. Natural approaches to prevention and treatment of infections of the lower urinary tract. Altern Med Rev. 2008;13(3):227-44.

5. Larsson B, Jonasson A, Fianu S. Prophylactic effect of UVA-E in women with recurrent cystitis: a preliminary report. Curr Ther Res. 1993;53:441-3.

6. Matsuda H, Nakamura S, Tanaka T, Kubo M. [Pharmacological studies on leaf of arctostaphylos uva-ursi (L.) Spreng. V. Effects of water extract from arctostaphylos uva-ursi (L.) Spreng. (Bearberry leaf) on the antiallergic anti-inflammatory activities of dexamethasone ointment.] Yakugaku Zasshi - J Pharm Soc Jpn. 1992;112(9):673-7.

7. Matsuda H, Nakata H, Tanaka T, Kubo M. [Pharmacological study on Arctostaphylos uva-ursi (L.) Spreng. II. Combined effects of arbutin and prednisolone or dexamethazone on immuno-inflammation] Yakugaku Zasshi. 1990;110(1):68-76.

Caffeine Anhydrous

1. Harland, B. F. (2000). Caffeine and nutrition. Nutrition, 16(7), 522-526.

2. Goldstein, E. R., Ziegenfuss, T., Kalman, D., Kreider, R., Campbell, B., Wilborn, C., ... & Wildman, R. (2010). International society of sports nutrition position stand: caffeine and performance. J Int Soc Sports Nutr, 7(1), 5.

3. Spriet, L. L. (1995). Caffeine and performance. International journal of sport nutrition, 5, S84-S84.

4. Astrup, A., Toubro, S., Cannon, S., Hein, P., Breum, L., & Madsen, J. (1990). Caffeine: a double-blind, placebo-controlled study of its thermogenic, metabolic, and cardiovascular effects in healthy volunteers. The American journal of clinical nutrition, 51(5), 759-767.

5. Hogervorst, E., Bandelow, S., Schmitt, J. A., Jentjens, R., Oliveira, M., Allgrove, J. E., ... & Gleeson, M. (2008). Caffeine improves physical and cognitive performance during exhaustive exercise.

6. Woolf, K., Bidwell, W. K., & Carlson, A. G. (2008). The effect of caffeine as an ergogenic aid in anaerobic exercise. International journal of sports nutrition,18(4), 412.

7. Stuart, G. R., Hopkins, W. G., Cook, C., & Cairns, S. P. (2005). Multiple effects of caffeine on simulated high-intensity team-sport performance. Medicine and science in sports and exercise, 37(11), 1998.

8. Beck, T. W., Housh, T. J., Schmidt, R. J., Johnson, G. O., Housh, D. J., Coburn, J. W., & Malek, M. H. (2006). The acute effects of a caffeine-containing supplement on strength, muscular endurance, and anaerobic capabilities. The Journal of Strength & Conditioning Research, 20(3), 506-510.

9. McLellan, T. M., Kamimori, G. H., Voss, D. M., Tate, C., & Smith, S. J. (2007). Caffeine effects on physical and cognitive performance during sustained operations. Aviation, space, and environmental medicine, 78(9), 871-877.

10. Lieberman, H. R., Tharion, W. J., Shukitt-Hale, B., Speckman, K. L., & Tulley, R. (2002). Effects of caffeine, sleep loss, and stress on cognitive performance and mood during US Navy SEAL training. Psychopharmacology, 164(3), 250-261.

11. Costill, D. L., Dalsky, G. P., & Fink, W. J. (1977). Effects of caffeine ingestion on metabolism and exercise performance. Medicine and science in sports, 10(3), 155-158.

12. Kovacs, E. M., Stegen, J. H., & Brouns, F. (1998). Effect of caffeinated drinks on substrate metabolism, caffeine excretion, and Performance. Journal of Applied physiology, 85(2), 709-715.

13. Acheson, K. J., Zahorska-Markiewicz, B., Pittet, P., Anantharaman, K., & Jéquier, E. (1980). Caffeine and coffee: their influence on metabolic rate and substrate utilization in normal weight and obese individuals. The American journal of clinical nutrition, 33(5), 989-997.

14. Dulloo, A. G., Geissler, C. A., Horton, T., Collins, A., & Miller, D. S. (1989). Normal caffeine consumption: influence on thermogenesis and daily energy expenditure in lean and postobese human volunteers. The American journal of clinical nutrition, 49(1), 44-50.

Yerba Matte

1. Bracesco, N., Sanchez, A. G., Contreras, V., Menini, T., & Gugliucci, A. (2011). Recent advances on Ilex paraguariensis research: minireview.Journal of ethnopharmacology, 136(3), 378-384.

2. De Morais, E. C., Stefanuto, A., Klein, G. A., Boaventura, B. C., De Andrade, F., Wazlawik, E., ... & da Silva, E. L. (2009). Consumption of yerba mate (Ilex paraguariensis) improves serum lipid parameters in healthy dyslipidemic subjects and provides an additional LDL-cholesterol reduction in individuals on statin therapy. Journal of agricultural and food chemistry,57(18), 8316-8324.

3. Arçari, D. P., Bartchewsky, W., Santos, T. W., Oliveira, K. A., Funck, A., Pedrazzoli, J., ... & Carvalho, P. D. O. (2009). Antiobesity Effects of yerba maté Extract (Ilex paraguariensis) in High‐fat Diet–induced Obese Mice.Obesity, 17(12), 2127-2133.

4. Matsumoto, R. L., Bastos, D. H., Mendonça, S., Nunes, V. S., Bartchewsky Jr, W., Ribeiro, M. L., & de Oliveira Carvalho, P. (2009). Effects of mate tea (Ilex paraguariensis) ingestion on mRNA expression of antioxidant enzymes, lipid peroxidation, and total antioxidant status in healthy young women.Journal of agricultural and food chemistry, 57(5), 1775-1780.

5. Da Silva, E. L., Neiva, T. J., Shirai, M., Terao, J., & Abdalla, D. S. (2008). Acute ingestion of yerba mate infusion (Ilex paraguariensis) inhibits plasma and lipoprotein oxidation. Food Research International, 41(10), 973-979.

Green tea

1. Effects of ingestion of a commercially available thermogenic dietary supplement on resting energy expenditure, mood state and cardiovascular measures. Outlaw J, Wilborn C, Smith A, Urbina S, Hayward S. J Int Soc Sports Nutr. 2013 Apr 30;10(1):25.

2. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. Dulloo AG, Duret C, Rohrer D, Girardier L, Mensi N, Fathi M, Chantre P, Vandermander J. Am J Clin Nutr. 1999 Dec;70(6):1040-5

3. Neurochemical and behavioral effects of green tea (Camellia sinensis): a model study. Mirza B, Ikram H, Bilgrami S, Haleem DJ, Haleem MA. Pak J Pharm Sci. 2013 May;26(3):511-6.

4. The effect of green tea extract on fat oxidation at rest and during exercise: evidence of efficacy and proposed mechanisms. Hodgson AB, Randell RK, Jeukendrup AE. Adv Nutr. 2013 Mar 1;4(2):129-40.

5. Metabolic response to green tea extract during rest and moderate-intensity exercise. Hodgson AB, Randell RK, Boon N, Garczarek U, Mela DJ, Jeukendrup AE, Jacobs DM. J Nutr Biochem. 2013 Jan;24(1):325-34.

Asparagus Extract

1. Dalvi SS, Nadkarni PM, Gupta KC. Effect of Asparagus racemosus (Shatavari) on gastric emptying time in normal healthy volunteers. J Postgrad Med 1990;36(2):91-94.

2. Escribano MM, Munoz-Bellido FJ, Serrano P, et al. Acute urticaria after ingestion of asparagus. Allergy 1998;53(6):622-623.

3. Wiboonpun N, Phuwapraisirisan P, Tip-pyang S. Identification of antioxidant compound from Asparagus racemosus. Phytother Res 2004;18(9):771-773

4. Yang CX, Huang SS, Yang XP, et al. Nor-lignans and steroidal saponins from Asparagus gobicus. Planta Med 2004;70(5):446-451

5. Huang X, Kong L. Steroidal saponins from roots of Asparagus officinalis. Steroids 2006;71:171-6.

6. Rodriguez R, Jaramillo S, Rodriguez G, et al. Antioxidant activity of ethanolic extracts from several asparagus cultivars. J Agric Food Chem 2005;53:5212-7.

Watermelon Extract

1. Tarazona-Díaz, M. P., Alacid, F., Carrasco, M., Martínez, I., & Aguayo, E. (2013). Watermelon juice: potential functional drink for sore muscle relief in athletes. Journal of agricultural and food chemistry, 61(31), 7522-7528.

2. Cutrufello, P. T., Gadomski, S. J., & Zavorsky, G. S. (2015). The effect of l-citrulline and watermelon juice supplementation on anaerobic and aerobic exercise performance. Journal of sports sciences, 33(14), 1459-1466.

3. Gul, S., Rashid, Z., & Sarwer, G. (2014). Citrullus Lanatus (Watermelon) as Diuretic Agent: An in vivo Investigation on Mice. American Journal of Drug Delivery and Therapeutics, 1(4), 89-92.

4. ISAWA, T. (1969). Diuretic effect of watermelon, part 2(Diuretic effective agents in watermelons).

Ginger Root

1. Ernst, E., & Pittler, M. H. (2000). Efficacy of ginger for nausea and vomiting: a systematic review of randomized clinical trials. British journal of anesthesia, 84(3), 367-371.

2. Chaiyakunapruk, N., Kitikannakorn, N., Nathisuwan, S., Leeprakobboon, K., & Leelasettagool, C. (2006). The efficacy of ginger for the prevention of postoperative nausea and vomiting: a meta-analysis. American journal of obstetrics and gynecology, 194(1), 95-99.

3. Smith, C., Crowther, C., Willson, K., Hotham, N., & McMillian, V. (2004). A randomized controlled trial of ginger to treat nausea and vomiting in pregnancy. Obstetrics & Gynecology, 103(4), 639-645.

4. Black, C. D., Herring, M. P., Hurley, D. J., & O'Connor, P. J. (2010). Ginger (Zingiber officinale) reduces muscle pain caused by eccentric exercise. The Journal of Pain, 11(9), 894-903.

5. Wu, K. L., Rayner, C. K., Chuah, S. K., Changchien, C. S., Lu, S. N., Chiu, Y. C., ... & Lee, C. M. (2008). Effects of ginger on gastric emptying and motility in healthy humans. European journal of gastroenterology & hepatology, 20(5), 436-440.

6. Wu, K. L., Rayner, C. K., Chuah, S. K., Changchien, C. S., Lu, S. N., Chiu, Y. C., ... & Lee, C. M. (2008). Effects of ginger on gastric emptying and motility in healthy humans. European journal of gastroenterology & Hepatology, 20(5), 436-440.

Juniper Extract

1. Bisset, NG. Juniper fructus. 1994;283-285.

2. Janku, I., Hava, M., and Motl, O. [Diuretic substance from juniper (Juniperus communis L.)]. Experientia 6-15-1957;13(6):255-256.

3. Stanic, G, Samarzija, I, and Blazevic, N. Time-dependent diuretic response in rats treated with juniper berry preparations. Phytother Res 1998;12:494-497.

Buchu Extract

1. Ernst E. Interactions between synthetic and herbal medicinal products Part 1: a systematic review of the indirect evidence. Perfusion 2000;13:4-15.

2. Lis-Balchin, M., Hart, S., and Simpson, E. Buchu (Agathosma betulina and A. crenulata, Rutaceae) essential oils: their pharmacological action on guinea-pig ileum and antimicrobial activity on microorganisms. J Pharm.Pharmacol. 2001;53(4):579-582

3. Fetrow CW, Avila JR. Professional's Handbook of Complementary & Alternative Medicines. 1st ed. Springhouse, PA: Springhouse Corp., 1999.

Taurine

1. Zhang, M., Izumi, I., Kagamimori, S., Sokejima, S., Yamagami, T., Liu, Z., & Qi, B. (2004). Role of taurine supplementation to prevent exercise-induced oxidative stress in healthy young men. Amino acids, 26(2), 203-207.

2. BOUCHAMA, A., YUSUF, A., AL-SEDAIRY, S. U. L. T. A. N., & EL-YAZIGI, A. D. N. A. N. (1993). Alteration of taurine homeostasis in acute heatstroke.Critical care medicine, 21(4), 551-554.

3. Gwacham, N., & Wagner, D. R. (2012). Acute effects of a caffeine-taurine energy drink on repeated sprint performance of American college football players. Int J Sport Nutr Exerc Metab, 22(2), 109-116.

4. Warskulat, U., Brookmann, S., Felsner, I., Brenden, H., Grether‐Beck, S., & Häussinger, D. (2008). Ultraviolet A induces transport of compatible organic osmolytes in human dermal fibroblasts. Experimental Dermatology, 17(12), 1031-1036.

Astragalus Centralpinus

1. Bai, F., Makino, T., Kono, K., Nagatsu, A., Ono, T., & Mizukami, H. (2013). Calycosin and formononetin from astragalus root enhance dimethylarginine dimethylaminohydrolase 2 and nitric oxide synthase expressions in Madin Darby Canine Kidney II cells. Journal of natural medicines, 67(4), 782-789.

2. Kuo, Y. H., Tsai, W. J., Loke, S. H., Wu, T. S., & Chiou, W. F. (2009). Astragalus membranaceus flavonoids (AMF) ameliorate chronic fatigue syndrome induced by food intake restriction plus forced swimming. Journal of Ethnopharmacology, 122(1), 28-34.

Chromium Polynicotinate

1. Parsons A, et al. A proof of concept randomized placebo-controlled factorial trial to examine the efficacy of St John's wort for smoking cessation and chromium to prevent weight gain on smoking cessation. Drug Alcohol Depend. (2009)

2. Abdollahi M, et al. Effect of chromium on glucose and lipid profiles in patients with type 2 diabetes; a meta-analysis review of randomized trials. J Pharm Pharm Sci. (2013)

3. Martin J, et al. Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes. Diabetes Care. (2006)

4. J Nutr Biochem. 2012 Apr;23(4):313-9. doi: 10.1016/j.jnutbio.2011.11.001. Molecular mechanisms of chromium in alleviating insulin resistance. Hua Y, Clark S, Ren J, Sreejayan N. College of Health Sciences, School of Pharmacy, Center for Cardiovascular Research and Alternative Medicine, University of Wyoming, Laramie, WY 82071, USA.

5. R. I. Press, J. Geller, and G. W. Evans The effect of chromium picolinate on serum cholesterol and apolipoprotein fractions in human subjects.

6. Harry G. Preuss1,*, Nadeem Talpur1, Vijaya Manohar1, Nagaveni Venkataramiah1 and Richard A. Anderson Chromium and hypertension

7. Stephen D. Anton, Christopher D. Morrison, William T. Cefalu, Corby K. Martin, Sandra Coulon, Paula Geiselman, Hongmei Han, Christy L. White, and Donald A. Williamson. Effects of Chromium Picolinate on Food Intake and Satiety

Potassium

1. Kanbay, M., Bayram, Y., Solak, Y., & Sanders, P. W. (2013). Dietary potassium: A key mediator of the cardiovascular response to dietary sodium chloride. Journal of the American Society of Hypertension, 7(5), 395-400.

2. Zhou, X., Zhang, Z., Shin, M. K., Horwitz, S. B., Levorse, J. M., Zhu, L., ... & Pan, Y. (2013). Heterozygous disruption of renal outer medullary potassium channel in rats is associated with reduced blood pressure. Hypertension, 62(2), 288-294.

Calcium

1. Barry et al. 2011; Acute Calcium Ingestion Attenuates Exercise-induced Disruption of Calcium Homeostasis

2. Paschoal et al. 2004; Nutritional status of Brazilian elite swimmers.

3. Venderley et al. 2006; Vegetarian diets : nutritional considerations for athletes.

4. Maughan et al. 2007; Nutrition and hydration concerns of the female football player.

5. Clarkson et al. 1995; Exercise and mineral status of athletes: calcium, magnesium, phosphorus, and iron.

6. Cinar et al. 2008; Testosterone levels in athletes at rest and exhaustion: effects of calcium supplementation.

Magnesium

1. Cinar, V., Polat, Y., Baltaci, A. K., & Mogulkoc, R. (2011). Effects of magnesium supplementation on testosterone levels of athletes and sedentary subjects at rest and after exhaustion. Biological trace element research, 140(1), 18-23.

2. van der Plas, A. A., Schilder, J. C., Marinus, J., & van Hilten, J. J. (2013). An explanatory study evaluating the muscle relaxant effects of intramuscular magnesium sulphate for dystonia in complex regional pain syndrome. The Journal of Pain, 14(11), 1341-1348.

3. Hatzistavri, L. S., Sarafidis, P. A., Georgianos, P. I., Tziolas, I. M., Aroditis, C. P., Zebekakis, P. E., ... & Lasaridis, A. N. (2009). Oral magnesium supplementation reduces ambulatory blood pressure in patients with mild hypertension. American journal of hypertension, 22(10), 1070-1075.

4. Golf, S. W., Bender, S., & Grüttner, J. (1998). On the significance of magnesium in extreme physical stress. Cardiovascular Drugs and Therapy,12(2), 197-202.

5. Carpenter, T. O., DeLucia, M. C., Zhang, J. H., Bejnerowicz, G., Tartamella, L., Dziura, J., ... & Cohen, D. (2006). A randomized controlled study of effects of dietary magnesium oxide supplementation on bone mineral content in healthy girls. The Journal of Clinical Endocrinology & Metabolism, 91(12), 4866-4872.

6. Held, K., Antonijevic, I. A., Künzel, H., Uhr, M., Wetter, T. C., Golly, I. C., ... & Murck, H. (2002). Oral Mg (2+) supplementation reverses age-related neuroendocrine and sleep EEG changes in humans. Pharmacopsychiatry,35(4), 135-143.

7. Brilla, L. R., & Haley, T. F. (1992). Effect of magnesium supplementation on strength training in humans. Journal of the American College of Nutrition,11(3), 326-329.

WARNING

California’s Proposition 65 entitles California consumers to special warnings.

WARNING: Cancer and Reproductive Harm - www.P65warnings.ca.gov/

Musclesport H2O

ADVANCED WATER DEPLETION*